Modulation of Wound Response and Soft Tissue Ingrowth into Synthetic and Allogeneic Implants with Platelet Rich Plasma

Principal Investigator: Anthony P. Sclafani, M.D., F.A.C.S.

Objective: This study is designed to evaluate the effects of various blood elements on wound healing and soft tissue ingrowth into a synthetic porous material and into an acellular human dermal graft.  Comparing the results in these two materials will give a greater understanding of the factors involved in tissue ingrowth into porous materials.

Project Co-Investigator is Gene Ukrainsky, M.D.

Contact Information: Anthony P. Sclafani, M.D., F.A.C.S., (212) 979-4200

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Funding: Aesthetic Technologies, Inc.

Selected Publications & Presentations:   

Sclafani AP, Fozo M, Romo T 3rd, McCormick SA. Strength and histology of periosteal fixation to bone after elevation. Arch Facial Plast Surg 2003; 5:63-66. [Abstract]

Sclafani AP, Romo T 3rd, Jacono AA. Rejuvenation of the aging lip with an injectable acellular dermal graft (Cymetra™). Arch Facial Plast Surg 2002; 4:252-257. [Abstract]

Sclafani AP, McCormick SA, Cocker R. Biophysical and microscopic analysis of homologous dermal and fascial materials for facial aesthetic and reconstructive uses. Arch Facial Plast Surg 2002; 4:164-171. [Abstract]

Sclafani AP. The multivectorial subperiosteal midface lift. Facial Plast Surg 2001; 17:29-36. [Abstract]

Sclafani AP, Romo T 3rd. Collagen, human collagen and fat: the search for a three-dimensional soft tissue filler. Facial Plast Surg 2001; 17:79-85. [Abstract]

Sclafani AP, Romo T 3rd, Jacono AA, McCormick SA, Cocker R, Parker A. Evaluation of acellular dermal graft (AlloDerm) for soft tissue augmentation: one year of clinical observations and histologic findings. Arch Facial Plast Surg 2001; 3:101-103. [Abstract]

Related Information: Other Research Projects in Facial Plastics and Reconstructive Surgery

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